Flea Free Ectoline duo dog 10-20kg pipette 2 pieces

Flea Free Ectoline duo dog 10-20kg pipette
RVG NL 116240 AV

FLEA FREE COMBO M, 134 mg/40 mg spot-on solution for medium dogs 10-20 kg
For use in flea infestations alone or together with tick infestations.

Against fleas:
Treatment and prevention of flea infestations (Ctenocephalides felis). One treatment
prevents further infestations for 7 weeks.
Prevention of flea reproduction by preventing the development
of adult fleas from flea eggs for 12 weeks after administration.

Against ticks:
Treatment of tick infestations (Ixodes ricinus).
One treatment provides sustained acaricidal efficacy against Ixodes ricinus for 2
weeks and against Dermacentor reticulatus and Rhipicephalus sanguineus for 4 weeks.
If some tick species (Dermacentor reticulatus, Rhipicephalus sanguineus) are present
at the time of administration of the veterinary medicinal product, not all ticks may be killed within the
first 48 hours.

What is this product used for
For use in flea infestations alone or together with tick infestations.

Do not use in
Do not use in rabbits, as side effects and even death may occur.
Do not use in animals known to be hypersensitive to the active substances or any of the excipients.

Use with extra caution in
Special warnings for each animal species for which the veterinary medicinal product is intended
Washing with shampoo or immersing the animal in water immediately after treatment may reduce the duration of action. The veterinary medicinal product remains effective against fleas for 5 weeks if the dog is washed with shampoo monthly after treatment. If the dog needs to be washed, it is better to do so before treatment.
Immersion in water, repeated at two times after treatment, had no effect on the adulticidal action against fleas, nor on the efficacy related to the prevention of the development of adult fleas from flea eggs.
The effect of immersion in water or washing the dog with shampoo on the efficacy of the veterinary medicinal product against ticks has not been evaluated.
At the beginning of control measures, in the event of an infestation, the dog bed, bedding and regularly used resting places such as rugs and upholstery should be treated with a suitable insecticide and vacuumed regularly.
To reduce flea contamination in the environment, all animals present in the household should be treated with a suitable flea control product.
The veterinary medicinal product does not prevent ticks from attaching to the animals. Transmission of infectious diseases by ticks cannot be completely ruled out if conditions are unfavorable. Immediate efficacy has been demonstrated against Ixodes ricinus, indicating that ticks of this species are likely to be killed within 48 hours after administration of the veterinary medicinal product.

If Dermacentor reticulatus or Rhipicephalus sanguineus ticks are present when the veterinary medicinal product is applied, these ticks may not be killed within the first 48 hours. Once the ticks are dead, they will usually fall off the animal. Remaining ticks should be carefully removed, ensuring that no mouthparts of the tick are left in the skin.

Ingestion during pregnancy and breastfeeding
Use during pregnancy, lactation or laying
Laboratory studies with fipronil and pyriproxyfen have yielded no data
indicating teratogenic or embryotoxic effects. The safety of this
veterinary medicinal product has not been demonstrated in pregnant and lactating dogs. Use during pregnancy and
lactation exclusively in accordance with the benefit/risk assessment of the treating veterinarian.

Other information
Special precautions for use in animals
For external use only.
Animals must be weighed accurately before treatment.
In the absence of safety data, the veterinary medicinal product should not be used in
puppies younger than 10 weeks and/or weighing less than 2 kg.
It is important to ensure that the contents of the pipette do not come into contact with the eyes or mouth
of the dogs being treated. In particular, oral intake due to licking
the application site by treated animals or animals that come into contact with treated
animals should be avoided.
Do not use the veterinary medicinal product on wounds or damaged skin.
In the absence of additional safety studies, treatment should not be repeated
at intervals of less than 4 weeks.
The use of the veterinary medicinal product has not been studied in sick and weakened animals.
Special precautions to be taken by the person administering the veterinary medicinal product to the
animals
The veterinary medicinal product may cause neurotoxicity.
The veterinary medicinal product may be harmful if swallowed.
Avoid ingestion, including hand-to-mouth contact.

Do not smoke, drink or eat during application.
In case of accidental ingestion, a doctor should be consulted immediately and the package leaflet
or label should be shown.
This veterinary medicinal product may cause irritation to the eyes and mucous membranes.
Avoid contact with skin, eyes and mouth, including hand-to-eye contact.
In case of accidental skin or eye contact, rinse thoroughly with water immediately.
If skin or eye irritation persists, a doctor should be consulted and the package leaflet or
label should be shown.
Wash hands after use.
Treated animals should not be touched until the application site is dry. Children should
not play with the treated animals until the application site is dry. Therefore, it is recommended
not to treat animals during the day but in the early evening and not to let recently treated animals
sleep with the owners, especially children.
Keep the pipettes in the original packaging until the time of application and dispose of used
pipettes immediately.
Other precautions
Fipronil and pyriproxyfen may have adverse effects on aquatic organisms.
Dogs should not swim in open water for 48 hours after treatment (see also
section 6.6).
The veterinary medicinal product may have adverse effects on painted, varnished or other
household surfaces or furniture. Allow the application site to dry before contact
with such materials occurs.

Overdose (symptoms, emergency procedures, antidota), if necessary
No serious side effects were observed in a safety study with 10-week-old
puppies, which were treated three times at 4-week intervals, with up to five times the maximum recommended dose and six times with the maximum recommended dose at 4-week intervals.
However, the risk of side effects occurring (see section 4.6) may increase with overdose, so animals should always be treated with the correct pipette size corresponding to the body weight

Active substances
Active substances 1.34 ml pipette:
Fipronil 134.0 mg
Pyriproxyfen 40.2 mg

Excipients
Butylhydroxyanisole E320
Butylhydroxytoluene E321
Diethylene glycol
monoethyl ether

Dosage
Volume Weight dog Fipronil (mg) Pyriproxyfen (mg)
0.67 ml 2-10 kg 67 20.1
1.34 ml 10-20 kg 134 40.2
2.68 ml 20-40 kg 268 80.4
4.02 ml 40-60 kg 402 120.6
For dogs > 60 kg, the appropriate combination of pipettes should be used.

Directions for use
Spot-on use

Method of administration:
Remove the pipette from the blister packaging. Hold the pipette upright. Tap the narrow end of the
pipette to ensure that all the contents are in the reservoir of the pipette.
Snap off the tip of the spot-on pipette along the break line.
Push the hair aside at the back of the dog's neck until the skin becomes visible.
Place the tip of the pipette directly against the skin and gently squeeze the pipette several times
to empty it. If necessary, the contents of the pipette can be administered to one or two additional sites
to prevent the veterinary medicinal product from running off the skin or being applied too
superficially to the coat, especially in large dogs.

The treatment consists of one pipette, with the possibility of repeating the application monthly.
For optimal control of flea and tick infestations and the reproduction of
fleas, the treatment schedule can be adapted to the epidemiological situation.
Read the package leaflet before use.
Pay attention to the maximum daily dose.

Responsible for placing on the market
ALFAMED, 13ème rue – LID, 06517 Carros Cedex, France