{"product_id":"vitals-curcumine-slcp-120-capsules","title":"Vitals Curcumin SLCP 120 Capsules","description":"\u003cstrong\u003eVitals Curcumin SLCP\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003eCurcumin is one of the most well-known and widely used herbal preparations. Curcumin is the main active ingredient of turmeric, an aromatic spice from the root of Curcuma longa. Turmeric originates from Indian cuisine, where, under the names koenjit or yellow root, it forms an important part of the famous curry dishes.\u003cbr\u003e\u003cbr\u003eCurcumin-SLCP™: a technological breakthrough\u003cbr\u003e The biggest challenge in developing curcumin preparations with optimal efficacy is overcoming the problems of its absorbability and bioavailability. After oral intake, 'unprocessed' curcumin is quickly converted in the intestine and liver into inactive metabolites, such as curcumin-glucuronide, which are rapidly excreted by the body. Verdure Sciences, the producer of Vitals' Curcumin-SLCP™, has, after years of research and collaboration with the University of California (UCLA), succeeded in solving these problems. Through their patented technology, they have managed to increase the absorption of curcumin by 65x and the bioavailability by no less than 285x (compared to standard curcumin preparations consisting of 95% curcumin). This breakthrough was achieved after testing many different formulations for their bioavailability in humans. The most optimal results were obtained with a formulation that is, in fact, inspired by Indian cuisine, where turmeric is mixed with oily components in the preparation of curry pastes. Their curcumin product, branded Longvida®, uses so-called Solid Lipid Curcumin Particles, where the curcumin is encapsulated in a fatty particle consisting of three long-chain fats also found in food, namely phosphatidylcholine, stearic acid, and ascorbyl palmitate.\u003cbr\u003e\u003cbr\u003eHow is Curcumin-SLCP™ absorbed into the body?\u003cbr\u003e Normally, curcumin is absorbed in the same way as most other nutrients (e.g., sugars and amino acids). In the intestinal epithelium, a first enzymatic conversion of biologically active curcumin into curcumin-glucuronide, an inactive metabolite, already takes place. Subsequently, the curcumin travels via the portal vein blood to the liver where it is further inactivated and then quite rapidly excreted. However, Curcumin-SLCP™ uses an alternative route of absorption into the body. Due to the unique way it is surrounded by fats, it is recognized by the body as such and treated in the same way as other long-chain fats in food. These are absorbed into the intestinal cells in chylomicrons (transport particles) and transported via the lymphatic system to the blood circulation. These chylomicrons initially do not pass through the liver but are transported via the blood to the various tissues and organs where they release their contents on site, under the influence of a fat-splitting enzyme (lipoprotein lipase). The curcumin in the chylomicron is still in the biologically active form, also called 'free' curcumin. In this form, it is released from the chylomicron and absorbed into the tissues and organs where it can exert its effect. Biologically active (free) curcumin itself is a fatty substance and can even cross the blood-brain barrier in this way, unlike the inactive metabolites of curcumin, and support the function of the central nervous system.\u003cbr\u003e\u003cbr\u003eAbsorbability versus bioavailability\u003cbr\u003e The absorbability of a certain substance is often discussed. This refers to the maximum blood level (Cmax) reached at a specific time after oral intake of a nutrient. Absorbability is part of bioavailability, but certainly doesn't tell the whole story. A nutrient can be absorbed very well and quickly reach a very high blood level, but then be broken down very quickly and removed from the body without having had sufficient time to be effective. It is important to also look at the development of the blood level over time and not just the moment the maximum blood level is reached. The point is how long the nutrient has been present in the blood in its biologically active form and how long it has had the opportunity to exert its effect. This says something about bioavailability, which is defined as that part of a nutrient that has been absorbed into the body and is available for use in certain bodily processes.\u003cbr\u003e\u003cbr\u003e Due to its high bioavailability, a low effective dose of Curcumin-SLCP™ is sufficient. And because it remains in the body as active curcumin for a long time, a single daily dose is sufficient. This offers many advantages for user-friendliness. Not everyone can tolerate high doses of curcumin well, and it is also easier to only have to remember to take a supplement once a day.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eComposition\u003cbr\u003e\u003c\/strong\u003e\u003ctable border=\"1\" cellpadding=\"1\" cellspacing=\"1\" style=\"width:400px\"\u003e\t\u003ctbody\u003e\t\t\u003ctr\u003e\t\t\t\u003ctd\u003e\u003cstrong\u003eComposition per daily dose of 1 capsule:\u003c\/strong\u003e\u003c\/td\u003e\t\t\t\u003ctd\u003e \u003c\/td\u003e\t\t\u003c\/tr\u003e\t\t\u003ctr\u003e\t\t\t\u003ctd\u003eCurcumin-SLCP™ (Longvida®)\u003c\/td\u003e\t\t\t\u003ctd\u003e400 mg\u003c\/td\u003e\t\t\u003c\/tr\u003e\t\t\u003ctr\u003e\t\t\t\u003ctd\u003eOf which curcumin\u003c\/td\u003e\t\t\t\u003ctd\u003e80 mg\u003c\/td\u003e\t\t\u003c\/tr\u003e\t\u003c\/tbody\u003e\n\n\n\u003c\/table\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eMay contain traces of\u003cbr\u003e\u003c\/strong\u003esoy\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eIngredients\u003cbr\u003e\u003c\/strong\u003eCurcumin (extract from Curcuma longa), stabilizers (stearic acid, phosphatidylcholine [from SOY lecithin]), hydroxypropyl methylcellulose (vegetable capsule), rice starch (Oryza sativa), maltodextrin, anti-caking agents (silicon dioxide, magnesium salts of fatty acids), antioxidant (ascorbyl palmitate).\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eUsage\u003cbr\u003e\u003c\/strong\u003eTake 1 capsule daily with a meal and water. Adhere to the recommended dosage. Suitable for vegetarians and vegans. Please note: Consult your doctor or pharmacist if using anticoagulants or other medications concurrently. Do not use during pregnancy, breastfeeding, in children under 18 years of age, with bile duct disorders, or existing liver problems. Turmeric can, in rare cases, cause liver problems. Consult your doctor if you experience jaundice or other unusual symptoms.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eStorage advice\u003c\/strong\u003e\u003cbr\u003eStore dry, sealed, and at room temperature.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eResponsible for marketing\u003c\/strong\u003e\u003cbr\u003eVitals BV\u003cbr\u003e\u003cbr\u003eThis product is a dietary supplement.\u003cbr\u003e\u003cbr\u003eDo not exceed the recommended dosage.\u003cbr\u003e\u003cbr\u003eA varied, balanced diet and a healthy lifestyle are important. A dietary supplement is not a substitute for a varied diet.\u003cbr\u003e\u003cbr\u003eKeep out of reach of young children.\u003cbr\u003e\u003cbr\u003eStore dry, sealed, and at room temperature, unless otherwise advised on the label.\u003cbr\u003e\u003cbr\u003eConsult an expert before using supplements in case of pregnancy, lactation, medication use, or illness.","brand":"Vitals","offers":[{"title":"120.00 Capsules","offer_id":63765616656714,"sku":"908277","price":56.71,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0924\/5497\/7866\/files\/8716717003396_A1N1.png?v=1790862678","url":"https:\/\/ithomepharma.com\/en\/products\/vitals-curcumine-slcp-120-capsules","provider":"AtHomePharma","version":"1.0","type":"link"}